Manipal Center for Infectious Diseases

Prasanna School of Public Health
Manipal Academy of Higher Education

MAC ID Members’ Publications

Patel DG, Kurian SJ, Miraj SS, Rashid M, Thomas L, Rodrigues GS, Banerjee M, Khandelwal B, Saravu K, Rao M. Effect of Vitamin D Supplementation in Type 2 Diabetes Patients with Tuberculosis: A Systematic Review. Curr Diabetes Rev. 2021 Sep 2.
Epub ahead of print. PMID: 34473618.

Vegivinti, C.T.R., Evanson, K.W., Lyons, H. Dr Kavitha Saravu, Efficacy of antiviral therapies for COVID-19: a systematic review of randomized controlled trials. BMC Infect Dis 22, 107 (2022).

Bhat, S. N., Kundangar, R., Ampar, N., Sait, A., Shenoy, P. A., Sukumar, C. A., & Saravu, K. (2022). The cocktail infection: anaerobic and aerobic co-Infections in tubercular vertebral osteomyelitis. F1000Research, 11(130), 130.

Gupta N, Wilson W, Ravindra P, Joylin S, Bhat R, Saravu K. Clinical profile, management and outcome of patients with leptospirosis during the times of COVID-19 pandemic: A prospective study from a tertiary care centre in South India. Infezioni in Medicina. 2021;29(3):393-401

Desai A, Gupta N, Korishetty L, Saravu K. Treatment outcomes of patients with tuberculosis and diabetes: Aprospective cohort study from India. J Mycobacteriol 2021;10:111-5.;year=2021;volume=10;issue=2;spage=111;epage=115;aulast=Desai

Kurian SJ, Miraj SS, Benson R, Munisamy M, Saravu K, Rodrigues GS, Rao M. Vitamin D Supplementation in Diabetic Foot Ulcers: A Current Perspective. Curr Diabetes Rev. 2021;17(4):512-521.

Prabhu, Anusha,Singhal Hardik ,Giri Nandagopal, M S Kulal, Reshma Peralam,Yegneswaran Prakash ,Mani Naresh Kumar . Knitting Thread Devices: Detecting Candida albicans Using Napkins and Tampons. ACS Omega 2021 6 (19), 12667-12675, DOI: 10.1021.

Muthunatarajan S, Basavaiah SH, Shenoy SM, Natarajan A, Mithra P, Suresh PK, Sreeram S. Discriminant value of automated leucocyte VCS parameters in the detection of tropical infections. J Clin Lab Anal. 2021 Apr;35(4):e23723

Gulati S, Chunduru K, Madiyal M, Setia MS, Saravu K.Validation of a Clinical Risk-scoring Algorithm for Scrub Typhus Severity in South India. Indian J Crit Care Med. 2021 May; 25(5):551-556. doi: 10.5005

Chatterjee A, Saravu K, Mukhopadhyay C, Chandran V. Neurological Melioidosis Presenting as Rhombencephalitis, Optic Neuritis, and Scalp Abscess with Meningitis: A Case Series from Southern India. Neurol India 2021;69:480-3.;year=2021;volume=69;issue=2;spage=480;epage=482;aulast=Chatterjee;type=2

Kurian et al. , Probiotics in Prevention and Treatment of COVID-19: Current Perspective and Future Prospects, Archives of Medical Research

Singhal, H. R., Prabhu, A., Giri Nandagopal, M. S., Dheivasigamani, T, Mani, N. K. (2021). One-dollar microfluidic paper-based analytical devices: Do-It-Yourself approaches. Microchemical Journal, 165.

John A, Gupta N, Saravu K. Paraparesis in a patient with advanced HIV infection: a diagnostic conundrum. BMJ Case Reports CP 2021;14:e240725.

Ruby, L.C., Kadavigere, R., Sheshadri, S. et al. Pulmonary aspergilloma on transthoracic ultrasound. Infection (2021).

Baliga, B.S., Baliga, S., Jain, A. Kulal N., Kumar M., Koduvattat N et al. Digitized smart surveillance and micromanagement using information technology for malaria elimination in Mangaluru, India: an analysis of five-year post-digitization data. Malar J 20, 139 (2021).

Nitin Gupta, Anupa John, Mohammed Safeer Kokkottil, Muralidhar Varma , Shashikiran Umakanth, Kavitha Saravu; Clinical profile and outcomes of asymptomatic vs. symptomatic travellers diagnosed with COVID-19: An observational study from a coastal town in South India;Drug Discoveries & Therapeutics ; Feb 2021;

Sukumar CA, Tomar S, Rai S, Saravu K. Pseudohypoparathyroidism: A Diagnosis That Traverses Specialities. Online J Health Allied Scs. 2020;19(3):12;

Pericherla S, Gupta N, Saravu K. Clinical profile and treatment outcomes of patients with brucellosis: a hospital-based cohort study from Southern India. Infez Med. 2021 Mar 1;29(1):65-69;

Shanbhag V, Chaudhuri S, Arjun NR, Gupta N, Umakanth S, Saravu K. Utility of awake prone positioning with low dose systemic corticosteroids in coronavirus disease 2019 acute respiratory distress syndrome patients: A case series. Indian J Respir Care 2021;10:100-6.

Nitin Gupta, Kiran Chunduru, Mohammad Safeer K, Kavitha Saravu, Clinical and laboratory profile of patients with Kyasanur Forest Disease: A Single-centre study of 192 patients from Karnataka, India. J of clinical Virology Jan 2021.

Gupta N, Saravu K, Varma M, Pm A, Shetty S, Umakanth S. Transmission of SARS-CoV-2 Infection by Children: A Study of Contacts of Index Paediatric Cases in India. J Trop Pediatr. 2020 Dec 5:fmaa081. doi: 10.1093/tropej/fmaa081.

Gupta N, Varma M, Saravu K. Difference in clinical presentation between the first and second phases of Kyasanur Forest disease: an experience from a teaching hospital in South India. Infez Med. 2020 Nov 1;28(4):597-602

Gupta N, Wilson W, Neumayr A, Saravu K. Kyasanur Forest disease: State-of-the-art review. QJM. 2020 Nov 16:hcaa310.

Sneha Deepak Mallya, Sravan Kumar Reddy T, Asha Kamath, Akhilesh Kumar Pandey, Kavitha Saravu, "Determinants of Metabolic Syndrome and 5-Year Cardiovascular Risk Estimates among HIV-Positive Individuals from an Indian Tertiary Care Hospital", AIDS Research and Treatment, vol. 2020.

Navya Vyas , Shilia Jacob Kurian , Debasis Bagchi , Mohan K. Manu , Kavitha Saravu , Mazhuvancherry Kesavan Unnikrishnan , Chiranjay M ukhopadhyay , Mahadev Rao, Sonal Sekhar Miraj; Vitamin D in Prevention and Treatment of COVID-19: Current Perspective and Future Prospects, J of the American College of Nutrition. 2020

Ali N, Gupta N, Saravu K. Malnutrition as an important risk factor for drug-induced liver injury in patients on anti-tubercular therapy: an experience from a tertiary care center in South India. Drug Discov Ther. 2020;14(3):135-138. doi:10.5582/ddt.2020.03029

Toyin Togun, Clive J. Hoggart, Schadrac C. Agbla, Marie P. Gomez, Uzochukwu Egere, Abdou K. Sillah, Binta Saidy, Francis Mendy, Madhukar Pai, Beate Kampmann, A three-marker protein biosignature distinguishes tuberculosis from other respiratory diseases in Gambian children, EBioMedicine,58, 2020.

Anusha Prabhu, Giri Nandagopal M. S.,Prakash Peralam Yegneswaran , Vijendra Prabhu, Ujjwal Verma, Naresh Kumar Mani ; Thread integrated smart-phone imaging facilitates early turning point colorimetric assay for microbes; RSC Adv., 2020, 10, 26853; DOI: 10.1039/d0ra05190j.!divAbstract

Prabhu, A., Giri Nandagopal, M.S., Peralam Yegneswaran, P. et al. Inkjet printing of paraffin on paper allows low-cost point-of-care diagnostics for pathogenic fungi. Cellulose (2020).

Sulis G, Adam P, Nafade V, Gore G, Daniels B, Daftary A, et al. (June 2020) Antibiotic prescription practices in primary care in low- and middle-income countries: A systematic review and meta-analysis. PLoS Med 17(6): e1003139

Pai, M. Tuberculosis: the story after the Primer. Nat Rev Dis Primers 6, 29 (2020).

Gupta N, Varma M, Sheshadri S, Saravu K. Pulmonary nocardiosis in an elderly man BMJ Case Reports CP 2020;13:e234090

Madlen Nash, Rajagopal Kadavigere, Jasbon Andrade, Cynthia Amrutha Sukumar, Kiran Chawla, Vishnu Prasad Shenoy, Tripti Pande, Sophie Huddart, M Pai, Saravu K. Deep learning, computer-aided radiography reading for tuberculosis: a diagnostic accuracy study from a tertiary hospital in India. Sci Rep 10, 210 (2020)

Nafade V, Huddart S, Sulis G, Saravu K et al. Over-the-counter antibiotic dispensing by pharmacies: a standardised patient study in Udupi district, India. BMJ Glob Health 2019;4:e001869. doi:10.1136/ bmjgh-2019-00186

Prasada Shobha, Bhat Archana, Bhat Sevitha, Mulki Shalini, Tulasidas Sanyuktha. Changing antibiotic susceptibility pattern in uropathogenic Escherichia coli over a period of 5 years in a tertiary care center. Infect Drug Resist. 2019 May 29;12:1439-1443. doi: 10.2147/IDR.S201849.

E. A. Talbot, M. Pai. Tackling drug-resistant tuberculosis: we need a critical synergy of product and process innovations; Int J Tuberc Lung Dis 2019; 23(7):774–782.

Saravu K, Pai M. Drug-resistant tuberculosis: Progress towards shorter and safer regimens. Lung India, 2019; 36:373-5.

Chetan Hasmukh Mehta, Reema Narayan, Gururaj Aithal, Sudharsan Pandiyan, Pritesh Bhat, Swapnil Dengale, Abhishek Shah, Usha Yogendra Nayak, Sanjay Garg, Molecular simulation driven experiment for formulation of fixed dose combination of Darunavir and Ritonavir as anti-HIV nanosuspension, Journal of Molecular Liquids, 293,2019

Commons RJ, Simpson JA, Thriemer K, Chu CS, Douglas NM, Abreha T, et al. The haematological consequences of Plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis. BMC Med. 2019;17(1):151.

Mathews, B.; Thalody, A.A.; Miraj, S.S.; Kunhikatta, V.; Rao, M.; Saravu, K. Adverse Effects of Fluoroquinolones: A Retrospective Cohort Study in a South Indian Tertiary Healthcare Facility. Antibiotics 2019, 8, 104.

Tilak, Amod, Smita Shenoy, Muralidhar Varma, Kamath A, Tripathy A, Sori R, Saravu K. "Opportunistic infection at the start of antiretroviral therapy and baseline CD4+ count less than 50 cells/mm3 are associated with poor immunological recovery" J Basic Clin Physiol Pharmacol, 30.2 (2019): 163-171

Mazumdar S, Satyanarayana S, Pai M. Self-reported tuberculosis in India: evidence from NFHS-4. BMJ Glob Health 2019;4:e001371. doi:10.1136/ bmjgh-2018-001371

Daftary A, Satyanarayana S, Jha N, et al Can community pharmacists improve tuberculosis case finding? A mixed methods intervention study in India BMJ Glob Health 2019;4:e001417

Gupta P, Guddattu V, Saravu K. Characterization of platelet count and platelet indices and their potential role to predict severity in malaria. Pathog Glob Health. 2019 Apr 9;1–8.

Chakrabarty S, Kumar A, Raviprasad K, Mallya S, Satyamoorthy K, Chawla K. Host and MTB genome encoded miRNA markers for diagnosis of tuberculosis. Tuberculosis. 2019;116:37–43.

Daniels, Benjamin, Ada Kwan, Srinath Satyanarayana, Ramnath Subbaraman, Ranendra K Das, Veena Das, Jishnu Das, Madhukar Pai. Use of standardised patients to assess gender differences in quality of tuberculosis care in urban India: a two-city, cross-sectional study Lancet Glob Health, Volume 7(5), e633 - e643 2/fulltext#articleInformation

Manda V, Josyula VR, Hariharapura RC. siRNA intervention inhibiting viral replication and delivery strategies for treating herpes simplex viral infection. VirusDis 2019.

Jennifer Furin, Helen Cox, Madhukar Pai, Tuberculosis, The Lancet, 2019, ISSN 0140-6736.

Kiran Jadhav, Rajeshwari HR, Swapnil Deshpande, Satveer Jagwani, Dinesh Dhamecha, Sunil Jalalpure, Karthikeyan Subburayan, Dwarkadas Baheti, Phytosynthesis of gold nanoparticles: Characterization, biocompatibility, and evaluation of its osteoinductive potential for application in implant dentistry, Materials Science and Engineering: C, Volume 93, 2018, 664-670, ISSN 0928-4931.

Aparajita C, Shipra R, Vasudeva G, Chiranjay M, Saravu K. Is Methicillin Resistant Staphylococcus Aureus infection associated with higher mortality and morbidity in hospitalized patients? A cohort study of 551 patients from South Western India. Risk Manag Healthc Policy. 2018:11 1-8.

Mudgal J, Mudgal PP, Kinra M, Raval R. Immunomodulatory role of chitosan‐based nanoparticles and oligosaccharides in cyclophosphamide treated mice. Scand J Immunol. 2019;e12749.

Saravu, K., Tellapragada, C., Kulavalli, S., Xavier, W., Umakanth, S., Brahmarouphu, G., Bhat, K. A pilot randomized controlled trial to compare the effectiveness of two 14-day primaquine regimens for the radical cure of vivax malaria in South India. 2018; Mal J, 17, 321.

Commons RJ, Simpson JA, Thriemer K, Humphreys GS, Abreha T, Alemu SG, et al. The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a World Wide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis. The Lancet Infectious Diseases [Internet]. 2018;3099(18):1–10.

Hakkimane SS, Shenoy VP, Gaonkar SL, Bairy I, Guru BR. Antimycobacterial susceptibility evaluation of rifampicin and isoniazid benz-hydrazone in biodegradable polymeric nanoparticles against Mycobacteriumm tuberculosis H37Rv strain. International Journal of Nanomedicine. 2018;13(July):1–16

Nathavitharana RR, Pai M. New strategies for inpatients with HIV and tuberculosis. The Lancet [Internet]. 2018;6736(18):18–9.

Pande T, Huddart S, Xavier W, Kulavalli S,Chen T, Pai M, Saravu K. (2018) Prevalence of diabetesmellitus amongst hospitalized tuberculosis patientsat an Indian tertiary care center: A descriptiveanalysis. PLoS ONE 13(7): e0200838

Pai M. Time for high-burden countries to lead the tuberculosis research agenda. PLoS Med 15(3): e1002544. (2018). 10.1371/journal.pmed.1002544

Performance of the Xpert HIV-1 Viral Load Assay: a Systematic Review and Meta-analysis

Time for high-burden countries to lead the tuberculosis research agenda

Tuberculosis: a Persistent Health Challenge for India

Point-of-Care Ultrasound for Extrapulmonary Tuberculosis in India: A Prospective Cohort Study in HIV-Positive and HIV-Negative Presumptive Tuberculosis Patients.

Immune thrombocytopenia secondary to tuberculosis: a case and review of literature

Severe vivax malaria: a prospective exploration at a tertiary healthcare centre in Southwestern India.

Fighting TB stigma: we need to apply lessons learnt from HIV activism

A 360-degree view of an ancient killer disease

Do rats pass the sniff tests?

Evaluating clinicians’ user experience and acceptability of LearnTB, a smartphone application for tuberculosis in India

Use of the GeneXpert tuberculosis system for HIV viral load testing in India

Tuberculosis innovations mean little if they cannot save lives

Reducing global tuberculosis deaths-time for India to step up

India's plan to eliminate tuberculosis by 2025:converting rhetoric into reality

Impact of fluoroquinolone treatment on delay of tuberculosis diagnosis: A systematic review and meta-analysis.

Quality of tuberculosis care in high burden countries: the urgent need to address gaps in the care cascade.

Therapeutic Assessment of Primaquine for Radical Cure of Plasmodium Vivax Malaria at Primary and Tertiary Care Centers in Southwestern India

Tuberculosis. Nature Reviews

Use of standardized patients to assess antibiotic dispensing for tuberculosis by pharmacies in urban India: a cross-sectional study S1473-3099(16)30215-8.

ID Related Meetings

12th International Conference on Emerging Infectious Diseases
October 22-23, 2021
Rome, Italy

For more details log on to:

18th Asia Pacific Congress of Clinical Microbiology and Infection
11-13 November 2021
Suntec, Singapore

For more details log on to:

The Immunotherapy for Infectious Diseases Conference - IIDC 2022
June 20-23th, 2022

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ID Publications

The Darwin Prospective Melioidosis Study: a 30-year prospective, observational investigation

Genetic Evaluation of Nosocomial Candida auris Transmission,local%20outbreak%20and%20transmission%20investigation

Characteristics of SARS-CoV-2 and COVID-19

Duration of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infectivity: When Is It Safe to Discontinue Isolation?

Association between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19 A Meta-analysis

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Poor Performance of Rapid Molecular Tests to Define Eligibility for the Shortcourse Multidrug-resistant Tuberculosis Regimen.

Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza

One Month of Rifapentine plus Isoniazid to Prevent HIV-Related Tuberculosis

Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)

Effect of the β-Lactamase Inhibitor Vaborbactam Combined with Meropenem against Serine Carbapenemase-Producing Enterobacteriaceae

2017 Infectious Diseases Society of America’s Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis

Weekends-off efavirenz-based antiretroviral therapy in HIV-infected children, adolescents, and young adults (BREATHER): a randomised, open-label, non-inferiority, phase 2/3 trial

Universal Mask Usage for Reduction of Respiratory Viral Infections after Stem Cell Transplant: A Prospective Trial

Addressing the challenges of diagnostics demand and supply: insights from an online global health discussion platform

Adjunctive Azithromycin Prophylaxis for Cesarean Delivery

Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America
DOI: 10.1093/cid/ciw118

The number of privately treated tuberculosis cases in India: an estimation from drug sales data

Zika Virus: Diagnostics for an Emerging Pandemic Threat

Zika Virus and the Guillain–Barré Syndrome — Case Series from Seven Countries

Chikungunya fever: A typical and lethal cases in the Western hemisphere. A Venezuelan experience

Against the odds, Sri Lanka eliminates malaria


MAC ID Newsletter 2019 -2021
MAC ID Newsletter 2018-2019
MAC ID Newsletter 2017-2018
MAC ID Newsletter 2016-2017

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